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US 12,391,689 B2Granted
Synthesis of key intermediate of KRAS G12C inhibitor compound
AssigneeAmgen Inc.
InventorsAndrew Thomas Parsons, Brian McNeil Cochran, William Powazinik, IV, Marc Anthony Caporini
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Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
Claims13
A composition, the composition comprising a compound of Formula 4:
- and a compound of Formula B:
Dependencies are inferred from the claim text.