Therapeutic compounds and methods
AssigneeActio Biosciences, Inc.
InventorsAshley Katana, John Otto Link
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Abstract
The disclosure provides a compound of formula I: or a salt thereof, wherein R1, R2, R4, L1, L2, and A have any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as TRPV4 antagonists.
Claims20
A method for treating a condition selected from a respiratory disease or disorder, a joint disease, pain, bladder dysfunction, and Mendelian disease, comprising administering to a subject a compound selected from the group consisting of:
- or a salt thereof.
A method for treating a condition selected from a respiratory disease or disorder, a joint disease, pain, bladder dysfunction, and Mendelian disease, comprising administering to a subject a pharmaceutical composition comprising a compound selected from the group consisting of:
- or a salt thereof, and a pharmaceutically acceptable excipient.
A method for treating a condition selected from a respiratory disease or disorder, a joint disease, pain, bladder dysfunction, and Mendelian disease comprising administering to a subject a compound which is:
- or a salt thereof.
Dependencies are inferred from the claim text.