Method and system for producing sterile solution filled containers

A cartridge assembly for a filling machine, the assembly comprising:

• a plurality of containers, each container including a volume and a stem connected to the volume;
• a connection line grid in fluid communication with each stem of the plurality of containers, the connection line grid including a first row connected to one or more containers of the plurality of containers and a second row connected to one or more containers of the plurality of containers;
• and
• a filter assembly coupled to the connection line grid;
• wherein the connection line grid includes a network of interconnected tubing defining a supply manifold, a return manifold, a first row, and a second row, the first row and the second row extending between the supply manifold and the return manifold.