# US 12,390,580 B2 · Medicament delivery device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,390,580 B2 - Document ID: US12390580B2 - Status: Granted - Kind: B2 - Application number: 17/688,971 - Filed: 2022-03-08 - Published: 2022-06-23 - Granted: 2025-08-19 - Earliest claimed: 2016-09-27 - Assignees: Sanofi-Aventis Deutschland GmbH - Applicants: Sanofi-Aventis Deutschland GMBH - Inventors: Michael Schabbach; Beate Franke; Andrew Nelson; Giuliano Pradel; Stefan Verlaak; Ilario Melzi - Web page: https://patentgrep.com/patent/US12390580B2 ## CPC - A61M 5/14248: {of the skin patch type} - A61M 5/148: flexible (A61M5/155 takes precedence) - A61M 5/2033: {Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287)} - A61M 5/206: {with automatic needle insertion} - A61M 2005/1402: {Priming} - A61M 2005/14252: {with needle insertion means} - A61M 2005/1426: {with means for preventing access to the needle after use} - A61M 2005/14272: {for emergency, field or home use, e.g. self-contained kits to be carried by the doctor} - A61M 2005/14506: {mechanically driven, e.g. spring or clockwork} - A61M 2005/2073: {preventing premature release, e.g. by making use of a safety lock} - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract The present disclosure relates to a medicament delivery device. The medicament delivery device comprises a housing, a dispensing mechanism and an actuator. The housing has first and second portions. The dispensing mechanism comprises a reservoir disposed in the housing. The dispensing mechanism is operable to dispense medicament from the reservoir when the reservoir contains medicament. The first portion of the housing comprises a distal end and the second portion is moveable towards the distal end from an initial position to a primed position. The dispensing mechanism is rendered inoperable when the second portion is in the initial portion. The actuator is actuatable to operate the dispensing mechanism when the second portion is in the primed position. ## Claims ### Claim 1 A medicament delivery device comprising: a housing comprising a first portion and a second portion, the first portion of the housing having a distal end and the second portion of the housing being moveable towards the distal end from an initial position to a second position, wherein when the second portion of the housing is in the second position, the medicament delivery device is in a primed position; a dispensing mechanism that comprises a reservoir disposed in the housing, the reservoir being a flexible bag, wherein the dispensing mechanism is operable to dispense a medicament from the reservoir when the reservoir contains the medicament; and an actuator, wherein actuation of the actuator is impeded such that the dispensing mechanism is rendered inoperable when the second portion is in the initial position, and the actuator is actuatable to operate the dispensing mechanism when the second portion is in the second position. ### Claim 2 (depends on 1) The medicament delivery device according to claim 1, wherein the reservoir is annular in shape. ### Claim 3 (depends on 1) The medicament delivery device according to claim 1, wherein the reservoir is a compressible bag. ### Claim 4 (depends on 1) The medicament delivery device according to claim 1, wherein the flexible bag is disposed in a recess in the housing. ### Claim 5 (depends on 1) The medicament delivery device according to claim 1, wherein the flexible bag abuts an inner proximal surface of the distal end of the first portion. ### Claim 6 (depends on 1) The medicament delivery device according to claim 1, wherein the dispensing mechanism further comprises a dispensing member and a biasing member configured to urge the dispensing member to move in a first direction relative to the housing to expel the medicament from the reservoir when the reservoir contains the medicament. ### Claim 7 (depends on 6) The medicament delivery device according to claim 6, wherein the biasing member is configured to resiliently deform when the second portion of the housing is moved from the initial position to the second position such that the biasing member exerts a biasing force on the dispensing member to urge the dispensing member in the first direction. ### Claim 8 (depends on 7) The medicament delivery device according to claim 7, further comprising a dispensing lock that is moveable between a locked state and an unlocked state, wherein the dispensing member is held in position relative to the housing against the biasing force of the biasing member when the dispensing lock is in the locked state, wherein the dispensing member is able to move in the first direction when the dispensing lock is in the unlocked state. ### Claim 9 (depends on 6) The medicament delivery device according to claim 6, wherein the flexible bag is located between a distal surface of the dispensing member and an inner proximal surface of the distal end of the first portion. ### Claim 10 (depends on 9) The medicament delivery device according to claim 9, wherein the flexible bag is compressed between the distal surface of the dispensing member and the inner proximal surface of the distal end of the first portion to dispense fluid from the flexible bag when the dispensing member moves in the first direction. ### Claim 11 (depends on 6) The medicament delivery device according to claim 6, wherein the dispensing member is moveable relative to the flexible bag. ### Claim 12 (depends on 1) The medicament delivery device according to claim 1, wherein the actuator is retracted into the housing when the second portion is in the initial position to prevent actuation of the actuator, and the actuator protrudes out of the housing when the second portion is in the second position. ### Claim 13 (depends on 1) The medicament delivery device according to claim 1, wherein the actuator comprises a push button. ### Claim 14 (depends on 1) The medicament delivery device according to claim 1, further comprising a needle that is configured to protrude from the distal end of the first portion. ### Claim 15 (depends on 14) The medicament delivery device according to claim 14, wherein the reservoir abuts the needle in a direction perpendicular to a longitudinal axis. ### Claim 16 (depends on 14) The medicament delivery device according to claim 14, wherein an interior of the flexible bag is fluidly connected to the needle when the second portion is in the second position. ### Claim 17 (depends on 16) The medicament delivery device according to claim 16, wherein the interior of the flexible bag is fluidly connected to the needle via a conduit when the second portion is in the second position. ### Claim 18 (depends on 1) The medicament delivery device according to claim 1, further comprising a latch configured to resist movement of the second portion relative to the first portion from the second position to the initial position. ### Claim 19 (depends on 1) The medicament delivery device according to claim 1, wherein the first portion of the housing comprises a filling port for supplying the reservoir with the medicament. ### Claim 20 (depends on 19) The medicament delivery device according to claim 19, wherein the filling port and/or the reservoir comprise a one-way valve. ### Claim 21 (depends on 1) The medicament delivery device according to claim 1, wherein the second portion of the housing comprises a filling port for supplying the reservoir with the medicament. ### Claim 22 (depends on 1) The medicament delivery device according to claim 1, wherein the medicament delivery device is a large volume device. ### Claim 23 (depends on 1) The medicament delivery device according to claim 1, wherein the reservoir contains the medicament. ### Claim 24 (depends on 1) The medicament delivery device according to claim 1, wherein the actuator is at least partially received in the second portion of the housing.