Solid phase carrier and kit
AssigneeFUJIFILM Corporation
InventorsKazuhei Kaneko, Yoshinori Kanazawa
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Abstract
An object of the present invention is to provide a solid phase carrier for carrying a bioactive substance, which achieves both the high non-specific adsorption inhibitory effect and high ligand binding amount. Another object of the present invention is to provide a kit for measuring a measurement target substance in a biosample, which includes the solid phase carrier. According to an embodiment of the present invention, a solid phase carrier for carrying a bioactive substance is provided which includes a copolymer present on a surface of the solid phase. The copolymer has a structural unit in which a hydrophilic group and a bioactive substance-reactive group are bonded to an acidic amino acid-derived group through a predetermined linking group.
Claims15
A solid phase carrier for carrying a bioactive substance, comprising:
- a copolymer of a structural unit represented by Formula (1) and a styrene,
- wherein the copolymer is present on a surface of the solid phase carrier,
- in the formula, R1 represents a hydrogen atom or a methyl group;
- X represents —NH— or —O—;
- Y represents —NH— or —O—;
- m represents an integer from 1 to 5;
- and
- wherein R2 represents a hydrophilic group and R3 represents a group represented by Formula (R-1) or wherein R3 represents a hydrophilic group and R2 represents a group represented by Formula (R-1),
- n represents an integer of 1 to 12, R4 represents a bioactive substance-reactive group, and * represents a position bonded to X or Y.
Dependencies are inferred from the claim text.