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US 12,385,885 B2Granted
State determination of a fluidic system
AssigneeDionex Softron GmbH
InventorMartin Rendl
Life of this patent
Estimating the term…
Abstract
A method for determining a state of a fluidic system can include measuring back pressures in the fluidic system at different times and determining a state of the fluidic system. The determination is based on at least the measured back pressures and on additional status information indicative of at least one status of the fluidic system at at least one of the different times.
Claims24
A method for determining a state of a fluidic system, the method comprising:
- measuring back pressures in the fluidic system at different times;
- and
- determining a state of the fluidic system, wherein the determination is based on at least the measured back pressures;
- wherein the step of determining a state of the fluidic system comprises comparing the measured back pressures to at least one reference;
- wherein the at least one reference is based on prior measurements of the back pressure.
2 more elements
A method for determining a state of a fluidic system, the method comprising:
- measuring back pressures in the fluidic system at different times;
- and
- determining a state of the fluidic system, wherein the determination is based on at least the measured back pressures;
- wherein the step of determining a state of the fluidic system further comprises determining a deviation when an absolute value between a measured back pressure and at least one reference exceeds a threshold,
- wherein the deviation is determined for the fluidic system assuming a first configuration,
- and wherein the method further comprises
- the fluidic system assuming a second configuration corresponding to a different fluidic pathway than the first configuration, and determining whether the deviation occurs in this second configuration, and
- thus narrowing down possible causes for the deviation.
5 more elements
A liquid chromatography system comprising:
- a pump configured to generate a liquid flow;
- a switching valve configured to switch between different configurations, wherein different components are fluidly connected to the pump depending on a position of the switching valve;
- a separation column;
- a fluid connection between the pump and the separation column;
- a data analysis unit configured to measure back pressures in the fluidic system at different times;
- and
- determine a state of the liquid chromatography system based on at least the measured back pressures,
- compare the measured back pressures to at least one reference to determine the state of the liquid chromatography system,
- wherein the at least one reference is based on prior measurements of the back pressure.
6 more elements
A liquid chromatography system comprising:
- a pump configured to generate a liquid flow;
- a switching valve configured to switch between different configurations, wherein different components are fluidly connected to the pump depending on a position of the switching valve;
- a separation column;
- a fluid connection between the pump and the separation column;
- wherein the system is configured to assume a first configuration and a second configuration corresponding to a different fluidic pathway than the first configuration;
- the system further comprising a data analysis unit configured to measure back pressures in the fluidic system at different times;
- and
- determine a state of the liquid chromatography system based on at least the measured back pressures, comprising
- determining a deviation when an absolute value between a measured back pressure and at least one reference exceeds a threshold,
- wherein the deviation is determined for the system assuming the first configuration, and
- determining whether the deviation occurs in the second configuration, and
- thus narrowing down possible causes for the deviation.
9 more elements
Dependencies are inferred from the claim text.