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US 12,385,878 B2Granted
Method for ion/ion reaction for ion mobility mass spectroscopy
AssigneeThe Trustees of Indiana University
InventorIan K. Webb
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Abstract
A mass spectrometry method comprises generating ions and separating the ions in an ion mobility cell. Some of the generated ions can be contacted with a mobility modifier. The ions can be analyzed with a mass analyzer.
Claims20
A mass spectrometry method, comprising:
- generating ions to form a mixture of ions comprising a first ion and a second ion, the first and second ions having overlapping mobilities,
- contacting, in a trap cell, the first ion and the second ion with a mobility modifier to form reaction products including a modified first ion and a modified or unmodified second ion, wherein the mobilities of the first modified ion and the modified or unmodified second ion are distinct from one another,
- separating in an ion mobility cell the modified first ion and the modified or unmodified second ion formed in the trap cell, and
- analyzing a mass spectrum of ions from the ion mobility cell.
1 more element
Dependencies are inferred from the claim text.