Back to results
US 12,384,832 B2Granted
Antibody-mediated neutralization of beta-lactamases
AssigneesChristopher Oelkrug, Andreas Schubert
InventorsChristopher Roland Oelkrug, Andreas Bernhard Joachim Schubert
Life of this patent
Estimating the term…
Abstract
Provided herein are antibodies, such as immunoglobulins Y (IgY) antibodies that inhibit beta-lactamase activity, e.g., TEM-1 beta-lactamase, as well as related compositions and methods of use thereof to treat infections by lactam-based antibiotic bacteria that produce beta-lactamase that can degrade antibiotics.
Claims5
An antigen composition comprising a peptide mixed with an adjuvant or mixed with a pharmaceutically acceptable carrier, wherein the peptide comprises any one of:
- (SEQ ID NO:
- 2)
- TRLDRWEPELN,
- (SEQ ID NO:
- 5)
- TRLDSWEPELN,
- (SEQ ID NO:
- 6)
- TRLDHWEPELN, or
- (SEQ ID NO:
- 9)
- TRLDRYEPELN,
- and wherein the peptide is between 10-20 amino acids in length.
10 more elements
Dependencies are inferred from the claim text.