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US 12,384,800 B2Granted
Antitumoral compounds
AssigneePharma Mar, S.A.
InventorsMaria del Carmen Cuevas Marchante, Andres Francesch Solloso, Valentin Martinez Barrasa
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Abstract
A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
Claims23
A pharmaceutical composition comprising a compound of Formula I:
- or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.
A process for obtaining a compound of Formula I:
- or a pharmaceutically acceptable salt thereof,
- comprising the step of reacting a compound of Formula II with a compound of Formula III to give a compound of formula IV:
- wherein
- X is —O—;
- R2 is a —C(═O)Ra group;
- R3 is hydrogen;
- R4 is hydrogen;
- and
- Ra is methyl.
6 more elements
A compound of Formula I:
- or a pharmaceutically acceptable salt thereof.
A method of treating cancer in a patient in need thereof, comprising administering to said patient a therapeutically effective amount of a compound of Formula I:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.