Recombinant herpes zoster vaccine composition and application thereof
AssigneeImmune-Path Biotechnology (Suzhou) Co., Ltd.
InventorsLi Shi, Zhi Zhang, Wenli Tian, Lin Liu, Xiaodong Sun, Wei Yang, Wei Li
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Abstract
Disclosed in the present invention are a recombinant herpes zoster vaccine composition and an application thereof. Compared with other combinations of antigens and adjuvants, the novel vaccine composition provided by the present invention has a more beneficial immune effect.
Claims4
A recombinant herpes zoster vaccine composition, comprising gE protein of varicella zoster virus (VZV) and a pharmaceutically acceptable combined adjuvant, wherein the pharmaceutically acceptable combined adjuvant is an aluminum adjuvant combined with a CpG adjuvant, a content of the gE protein is 50-100 μg, a content of the aluminum adjuvant is 225-600 μg, and a content of the CpG adjuvant is 300-900 μg.
Dependencies are inferred from the claim text.