Vaccine to protect a pig against Actinobacillus pleuropneumoniae
AssigneeIntervet Inc.
InventorsMaarten Hendrik Witvliet, Johanna Jacoba Elisabeth Bijlsma
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Abstract
The present invention pertains to a vaccine to protect a pig against an infection with Actinobacillus pleuropneumoniae, the vaccine comprising an RTX toxin of Actinobacillus pleuropneumoniae recombinantly expressed by a baculovirus, and a pharmaceutically acceptable carrier.
Claims6
A method of protecting a pig against an infection with Actinobacillus pleuropneumoniae by administering to the pig a dose of a vaccine, wherein the vaccine comprises an isolated and purified 110 kDa ApxI toxin of Actinobacillus pleuropneumoniae expressed recombinantly by a baculovirus, wherein the vaccine is without LPS or another hetero-toxin, and wherein the vaccine further comprises an adjuvant.
Dependencies are inferred from the claim text.