Acid resistant banding solution for two piece hard capsules
AssigneeCapsugel Belgium NV
InventorTakahisa Takubo
Life of this patent
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Abstract
The present disclosure relates to acid resistant banding solutions for two piece hard capsules, and methods of making the same. The present disclosure also relates, in part, to a method for banding such capsules which provides an acid resistant seal between the capsule parts and achieves an increased acid resistance in vitro. The instant disclosure further relates to a capsule sealing solution formula that comprises shellac ink or shellac ink vehicle component.
Claims15
An acid resistant band formed from an acid resistant banding composition, wherein the acid resistant band comprises from about 20 wt % to about 95 wt % shellac based on the total weight of the acid resistant banding composition, wherein the acid resistant band is formed on a two-piece hard capsule and is formed only at a juncture of a telescopically engaged cap and body of the two-piece hard capsule.
A sealed two-piece hard capsule comprising:
- a telescopically engaged cap and body forming a two-piece hard capsule shell;
- an acid resistant band formed only at the juncture of the telescopically engaged cap and body, wherein the acid resistant band is formed from an acid resistant banding composition and comprises about 20 wt % to about 95 wt % shellac based on the total weight of the acid resistant banding composition;
- wherein the two piece hard capsule shell is formed from a material selected from polyacrylates, polymethacrylates, polyvinylpyrrolidone, poly (vinyl acetate), various starches, corn products, pectin, alkoxylated celluloses, polyesters, polyethers, proteins, nucleic acids, albumin, gelatin, pullulan, chitin, chitosan, agar, starch, collagen, dextran and modified dextrans, polysaccharides, polylactide/polyglycolide, polyalkylcyanoacrylates, polyacrylamide, polysorbates, polyethylene ethers, polyethylene esters, polyoxyethylene/polyoxypropylene block polymers, cellulose acetophthalate, hydroxypropylmethyl cellulose, cellulose esters, cellulose diesters, cellulose triesters, cellulose ethers, cellulose ester-ether, cellulose acylate, cellulose diacylate, cellulose triacylate, cellulose acetate, cellulose diacetate, cellulose triacetate, cellulose acetate propionate, cellulose acetate butyrate, methyl cellulose, ethyl cellulose, hydroxyethyl cellulose, propyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose (hypromellose), lower-substituted hydroxypropyl cellulose, carboxymethyl cellulose, and mixtures thereof.
Dependencies are inferred from the claim text.