Compositions and methods for preventing or ameliorating neonatal HSV infection
AssigneesTrustees of Dartmouth College, Duke University
InventorsMargaret E. Ackerman, Iara M. Backes, David A. Leib, Chaya D. Patel, Michael Anthony Moody
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Abstract
The present disclosure relates to compositions and methods for treating or preventing neonatal herpes simplex virus (HSV) infection and/or the neurological and/or non-neurological sequelae thereof.
Claims23
A method for protecting offspring against neurological or behavioral consequences of neonatal herpes simplex virus (HSV) infection, the method comprising:
- administering to a maternal subject an anti-HSV antibody, wherein the maternal subject is HSV seronegative and the maternal subject is pregnant.
A method for protecting offspring against neurological or behavioral consequences of neonatal herpes simplex virus (HSV) infection, the method comprising:
- administering to a maternal subject an immunogenic product comprising one or more HSV antigens, wherein the maternal subject is HSV seronegative and the maternal subject is pregnant.
A method for protecting offspring against neurological disease associated with neonatal herpes simplex virus (HSV) infection, the method comprising:
- administering to a pregnant subject an anti-HSV antibody, wherein the neurological disease associated with neonatal HSV infection is anxiety or a mood disorder and wherein the pregnant subject is HSV seronegative or has a latent HSV infection.
Dependencies are inferred from the claim text.