Treatment intervals for use of compositions comprising energy absorbing materials for dermatological applications
AssigneeCoronado Aesthetics, LLC
InventorsAnthony V. Lando, Dilip Paithankar, Erin C. Keller, Todd J. Meyer
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Abstract
The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g. massage), acoustic vibration in the range of 10 Hz-20 kHz, ultrasound, alternating suction and pressure, and microjets. The method of treatment is performed and then, depending upon the desired clinical outcome, repeated after a treatment response interval has elapsed.
Claims18
A method of treating or ameliorating a follicular skin disease of a subject, the method comprising:
- topically applying a formulation comprising a particle between about 1 and about 5 microns comprising a light absorbing material to a subject's skin;
- facilitating delivery of the material into a hair follicle by ultrasound-created microjets in the formulation, wherein ultrasound energy used to create the ultrasound-created microjets in the delivery is at a frequency in a range of 30 kHz to 50 kHz;
- irradiating the particle with light, thereby heating the particle for treating or ameliorating the follicular skin disease;
- waiting until a response interval has passed;
- and
- repeating the topically applying, facilitating and irradiating steps.
Dependencies are inferred from the claim text.