Disposable components for fluid line autoconnect systems and methods

A fluid handling cassette for use in a medical infusion system, the fluid handling cassette comprising:

• a generally planar body having a first pump chamber and a second pump chamber each formed as a depression in a first side of the body, each pump chamber of the first pump chamber and the second pump chamber having a first port and a second port connecting a respective pump chamber of the first pump chamber and the second pump chamber to a second side of the body;
• a plurality of valve wells on the first side of the body including a first group of valve wells and a second group of valve wells, valve wells in the first group of valve wells each comprising a valve port and an opening, both of the valve port and the opening connecting a respective valve well of the first group of valve wells to the second side of the body;
• valve wells in the second group of valve wells each comprising a valve port connecting a respective valve well of the second group of valve wells to the second side of the body, each of the valve wells of the second group of valve wells being connected to the second side of the body only by a respective valve port of the valve ports of the valve wells of the second group of valve wells;
• a plurality of cassette ports including at least three cassette ports located on a first end of the body and at least three cassette ports on a second end of the body, each of the plurality of cassette ports being directly connected to a respective valve well of the second group of valve wells;
• and
• a first fluid flowpath and a second fluid flowpath on the second side of the body, each fluid flowpath of the first fluid flowpath and the second fluid flowpath connected to the first port or the second port of a respective pump chamber of the first pump chamber and the second pump chamber via a valve well of the first group of valve wells;
• wherein each cassette port of the plurality of cassette ports is connected to one fluid flowpath of the first fluid flowpath and the second fluid flowpath via the respective valve well of the second group of valve wells.