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US 12,377,102 B2Granted
Compounds for the prevention and treatment of medical disorders and uses thereof
AssigneeGalectin Sciences, LLC
InventorsRaphael Nir, Eliezer Zomer, Peter G. Traber, Joseph M. Johnson, Ryan George, Sharon Shechter
Life of this patent
Estimating the term…
Abstract
Aspects of the invention relate to compounds, pharmaceutical compositions, methods for the manufacturing of compounds and methods for treatment of various disorders mediated at least in part by one or more galectins.
Claims3
A compound of Formula I or a pharmaceutically acceptable salt or solvate thereof:
- Formula I:
- wherein Y linkage is (—CH═);
- wherein Z is a carbon;
- wherein R1 is hydrogen, oxygen, amine, carboxyl, C1-C6 alkyl, C1-C4 alkoxy, aryl, halogen, trifluoromethyl, dinitromethyl or a combination of the foregoing;
- and
- wherein R2, R3 or R2 and R3 are hydrogen, hydroxyl, amine, carboxyl, C1-C6 alkyl, C1-C4 alkoxy, or halogen, provided that when R1 is hydrogen, R2 and R3 are not hydrogen, when R1 and R2 are hydrogen, R3 is not a methoxy group, or when R1 and R3 are hydrogen, R2 is not a methoxy group.
3 more elements
Dependencies are inferred from the claim text.