Delivery system matrices
AssigneeWellomics LLC
InventorMark J. Neveu
Life of this patent
Estimating the term…
Abstract
This invention relates to delivery matrix compositions (e.g., dietary products or pharmaceuticals) and related methods. In particular, the disclosure relates to delivery matrix compositions that include temperature-dependent O/W emulsion complexes, low viscosity sheared fluid gels, and viscous hydrogels that can facilitate the delivery of a wide range of substances to the gastrointestinal tract (e.g., small intestine) of a subject.
Claims26
A dietary product or oral pharmaceutical comprising an oil-in-water (O/W) emulsion complex comprising a water phase and an oil phase, ascorbyl palmitate, a high hydrophile-lipophile balance (HLB) saponin with a HLB of greater than or equal to 10, and a Glycyrrhiza glabra (licorice) root saponin, wherein the concentration of ascorbyl palmitate is 0.15-4.5 mg/gm, wherein the concentration of the high HLB saponin is 0.01-1.6 mg/gm, and wherein the concentration of Glycyrrhiza glabra root saponin is 0.02-160 mg/gm.
A dietary product or oral pharmaceutical comprising a gel delivery matrix comprising:
- (a) an O/W emulsion complex that is thixotropic with a glass-transition temperature range between 50-80° C.;
- (b) a pectin with 10-40% ester groups;
- and
- (c) a cation,
- wherein the concentration of pectin is 1-10 mg/gm or.
A dietary product or oral pharmaceutical comprising a hydrogel delivery matrix comprising:
- (a) gel delivery matrix or an O/W emulsion complex that is thixotropic with a glass-transition temperature range between 50-80° C.;
- (b) at least one beta glucan;
- and
- (1) any one or more of acacia gum, a hydrocolloid, and a molecule that reduces syneresis and increases viscosity;
- and/or
- (2) a fructooligosaccharide and/or mucilaginous extract, hydrocolloid, or dietary fiber;
- wherein the molecule that reduces syneresis and increases viscosity is a plant extract, dietary fiber, protein, cyclodextrin, beet pectin or high methoxy calcium insensitive pectin, or cold set plant extract, and
- wherein the concentration of the beta glucan is 2-30 mg/gm.
Dependencies are inferred from the claim text.