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AssigneeInstitute of Animal Sciences of Caas
InventorsHong Jia, Hongfei Zhu, Weifeng Yuan, Shaohua Hou, Xiaoyu Guo, Yitong Jiang, Qianqian Feng, Zhaoyang Wang, Ting Xin
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A heavy-chain variable region sequence of the nanobody CPV-VHH-H1 has the amino acid sequence set forth in SEQ ID NO: 1; and a gene encoding the nanobody CPV-VHH-H1 has the nucleotide sequence set forth in SEQ ID NO: 2. A nanobody immune library of the CPV is constructed by a phage display technology, a specific anti-CPV nanobody CPV-VHH-H1 is obtained by screening, and it is verified by experiments that the nanobody may specifically bind to the CPV. A new nanobody preparation for use in clinical diagnosis and treatment of the CPV can be developed, and a certain theoretical reserve is provided for applying the nanobody to the field of veterinary biological products.
A canine parvovirus (CPV) antibody CPV-VHH-H1, wherein a heavy-chain variable region sequence of the antibody has the amino acid sequence set forth in SEQ ID NO:
Dependencies are inferred from the claim text.