Filtration system for cell removal systems and methods of using the same
AssigneeEMD Millipore Corporation
InventorsClinton Boyd Pepper, David Andrew Hansen
Life of this patent
Estimating the term…
Abstract
A filtration system can include a loading member configured to receive a plurality of filtration members which can be sequentially moved from a non-active position in which a respective one of the plurality of filtration members is not in fluid communication with a sample flow path of the cell removal system, to an active position in which the respective filtration member is in fluid communication with the sample flow path, and to a discarded position in which the respective filtration member has been removed from fluid communication with the sample flow path.
Claims18
A filtration system for use with a cell removal system, comprising:
- a loading member, having a first slot and a second slot, the second slot for engaging with a cleaning shell, wherein the loading member is a rotary-indexed magazine, configured to receive a plurality of filtration members, wherein the plurality of filtration members are vertically arranged on the loading member, each of the plurality of filtration members including a filtration inlet, a filtration outlet, and a horizontal filtration flow path that extends from the filtration inlet to the filtration outlet;
- at least one actuator configured to move the plurality of filtration members, sequentially, from a non-active position in which a respective one of the plurality of filtration members is not in fluid communication with a sample flow path of the cell removal system, to an active position in which a respective filtration member is in fluid communication with the sample flow path, and to a discarded position in which the respective filtration member has been removed from fluid communication with the sample flow path, wherein the loading member, the first slot, and the second slot are arranged vertically along a long axis to sequentially move the plurality of filter members from an inactive position to an active position and to a discard position.
A cell removal system comprising:
- a sample flow path having a sample inlet for receiving a sample of a cell-containing solution;
- a vertically-oriented loading member configured to receive a plurality of horizontally-oriented filtration members, each of the plurality of filtration members including filtration inlet, a filtration outlet, and a filtration flow path that extends from the filtration inlet to the filtration outlet;
- at least one actuator configured to move the plurality of filtration members, sequentially, from a non-active position in a first slot in which a respective one of the plurality of filtration members is not in fluid communication with a sample flow path of the cell removal system, to an active position in a second slot opposite the first slot in which a respective filtration member is in fluid communication with the sample flow path, and to a discarded position in a waste slot in which the respective filtration member has been removed from fluid communication with the sample flow path, wherein the loading member, the first slot, and the second slot are arranged vertically along a long axis to sequentially move the plurality of filter members from an inactive position to an active position and to a discard position.
Dependencies are inferred from the claim text.