RSV virus-like particles and methods of use thereof
AssigneesEmory University, Children's Healthcare of Atlanta, Inc., Wisconsin Alumni Research Foundation
InventorsBinh Ha, Larry J. Anderson, Elizabeth R. Wright
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Abstract
The present disclosure relates to virus-like particles and vaccine compositions for inducing immunity and preventing respiratory syncytial virus (RSV) infection. Specifically, the disclosure provides virus like-particles (VLPs) for use in inducing immunity to respiratory syncytial virus (RSV) infections or symptoms thereof, wherein the VLP comprising a respiratory RSV matrix protein (M) and an RSV M2-1 protein, a glycoprotein (G), a fusion protein (F), and/or a phosphoprotein (P).
Claims8
A virus like particle (VLP) comprising a respiratory syncytial virus (RSV) M protein, an RSV P protein, an RSV F protein, and an RSV G protein, wherein
- the RSV F protein comprises SEQ ID NO:
- 23 or
- the RSV G protein comprises SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.