Methods and systems for non-destructive estimation of scattering particle size
AssigneeThe General Hospital Corporation
InventorsSeemantini Nadkarni, Zeinab Hajjarian-Kashany
Life of this patent
Estimating the term…
Abstract
A method for non-destructively estimating an average size of scattering particles in a sample, including: transmitting, using a coherent light source, polarized light to the sample; obtaining, using a detector, polarized light reflected from the sample, the polarized light comprising a parallel polarized component and a perpendicular polarized component; determining, using a processor, speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component; and estimating, using the processor, the average size of scattering particles in the sample based on the speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component.
Claims20
A method for non-destructively estimating an average size of scattering particles in a sample, comprising:
- transmitting, using a coherent light source, polarized light to the sample;
- obtaining, using a detector, polarized light reflected from the sample as a function of time, the polarized light comprising a parallel polarized component and a perpendicular polarized component;
- determining, using a processor, speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component,
- wherein determining the speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component comprises determining relaxation curves for the parallel polarized component and the perpendicular polarized component based on the polarized light reflected from the sample as a function of time;
- and
- estimating, using the processor, the average size of scattering particles in the sample based on the relaxation curves for the parallel polarized component and the perpendicular polarized component.
An apparatus for non-destructively estimating an average size of scattering particles in a sample, comprising:
- a coherent light source;
- a detector;
- and
- a processor in communication with the coherent light source and the detector, the processor being configured to:
- control the coherent light source to transmit polarized light to the sample,
- control the detector to obtain polarized light reflected from the sample,
- the polarized light comprising a parallel polarized component and a perpendicular polarized component,
- determine speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component,
- wherein determining the speckle decorrelation rates for the parallel polarized component and the perpendicular polarized component comprises determining relaxation curves for the parallel polarized component and the perpendicular polarized component based on the polarized light reflected from the sample as a function of time, and
- estimate the average size of scattering particles in the sample based on the relaxation curves for the parallel polarized component and the perpendicular polarized component.
Dependencies are inferred from the claim text.