Benzothia(di)azepine compounds and their use as bile acid modulators

A compound of formula (I)

• wherein
• M is selected from —CH2— and —NR5—;
• R1 is C1-4 alkyl;
• R2 is independently selected from the group consisting of hydrogen, halogen, hydroxy, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, cyano, nitro, amino, N—(C1-4 alkyl)amino, N,N-di(C1-4 alkyl)amino, C1-6 alkylcarbonylamino, C3-6 cycloalkylcarbonylamino, N—(C1-4 alkyl)aminocarbonyl, N,N-di(C1-4 alkyl)aminocarbonyl, C1-4 alkyloxycarbonylamino, C3-6 cycloalkyloxycarbonylamino, C1-4 alkylsulfonamido and C3-6 cycloalkylsulfonamido;
• n is an integer 1, 2 or 3;
• R3 is selected from the group consisting of hydrogen, halogen, cyano, C1-4 alkyl, C3-6 cycloalkyl, C1-4 alkoxy, C3-6 cycloalkyloxy, C1-4 alkylthio, C3-6 cycloalkylthio, amino, N—(C1-4 alkyl)amino and N,N-di(C1-4 alkyl)amino;
• R4A and R4B are each independently selected from the group consisting of hydrogen, halogen, hydroxy, C1-4 alkyl and C1-4 alkoxy;
• or R4A and R4B, together with the carbon atom to which they are attached, form a 3- to 5-membered saturated carbocyclic ring;
• R4C and R4D are each independently selected from the group consisting of hydrogen and C1-4 alkyl;
• and
• R5 is selected from the group consisting of hydrogen and C1-4 alkyl;
• or a pharmaceutically acceptable salt thereof.