Filtration system for preparation of fluids for medical applications

A system for filling multiple a plurality of containers, the system comprising:

• a plurality of manifolds, each manifold having a manifold inlet and multiple manifold outlets;
• a filter including a filter inlet port and multiple filter outlet ports, each of the multiple filter outlet ports being pre-attached to a respective manifold of the plurality of the manifolds through the manifold inlet of the respective manifold, and each of the multiple manifold outlets of the respective manifold being pre-attached to a respective container of the plurality of the containers by a respective filling line of each container of the plurality of the containers;
• the plurality of the containers, each container of the plurality of the containers having an interior, each of the respective filling lines being connected to a respective interior;
• and
• the respective filling lines, wherein all of the respective filling lines are fluidly sealed to the filter outlet ports, to manifold inlets, to the manifold outlets, and to the containers of the plurality of the containers, such that the interiors of the plurality of the containers are isolated from an external environment except the filter inlet port, via the filter, forming a combined interior volume which is sterile, an interior volume of the plurality of the manifolds being included in said combined interior volume.