Implantable paste and its use

An antibacterial, implantable paste comprising

• (a) bioactive glass powder having a size distribution of 0.5-45 μm in an amount of 10-30 wt-% of the total weight of the bioactive glass,
• (b) bioactive glass granules having a size distribution between 100 and 4000 um in an amount of 90-70 wt-% of the total weight of the bioactive glass,
• (c) low molecular weight polyethylene glycol having a molecular weight range of 200-700 g/mol,
• (d) medium molecular weight polyethylene glycol having a molecular weight range of 700-2500 g/mol,
• (e) high molecular weight polyethylene glycol having a molecular weight range of 2500-8000 g/mol and
• (f) glycerol,
• wherein the composition of the bioactive glass is 45-55 weight-% of SiO2, 20-25 weight-% of Na2O, 18-25 weight-% of CaO and 3-6 weight-% of P2O5, with the proviso that the molecular weight of the low molecular weight polyethylene glycol and of the medium molecular weight polyethylene glycol differ from each other by at least 80 g/mol and that the molecular weight of the medium molecular weight polyethylene glycol and of the high molecular weight polyethylene glycol differ from each other by at least 300 g/mol;
• wherein said implantable paste is antibacterial in the absences of an antibiotic;
• wherein the total amount of bioactive glass is 50-79 wt-% of the total weight of the paste;
• wherein the amount of low molecular weight polyethylene glycol having a molecular weight range of 200-700 g/mol (c) is 2-15 wt-% of the total weight of the paste, the amount of medium molecular weight polyethylene glycol having a molecular weight range of 700-2500 g/mol (d) is 8-47 wt-% of the total weight of the paste and the amount of high molecular weight polyethylene glycol (e) is 1-10 wt-% of the total weight of the paste;
• wherein the total amount of polyethylene glycols is 20-50 wt-% of the total weight of the paste and that the amount of glycerol (f) is up to 10 wt-% of the total weight of the paste;
• and
• wherein the implantable bone paste does not comprise bioactive glass powder and bioactive glass granules that are spheres.