Microbiota sequence variants of tumor-related antigenic epitopes
AssigneeEnterome S.A.
InventorsLaurent Chene, Alessandra Cervino, Francesco Strozzi, Celia Mendez, Christophe Bonny
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Abstract
The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
Claims14
A medicament comprising a human microbiota peptide sequence variant of a human tumor-related antigenic epitope sequence, wherein the human microbiota peptide sequence variant comprises or consists of an amino acid sequence according to any one of SEQ ID NOs:
- 6-16.
Dependencies are inferred from the claim text.