# US 12,364,731 B2 · Method for treating or alleviating autoimmune-related diseases

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- Number: US 12,364,731 B2
- Document ID: US12364731B2
- Status: Granted
- Kind: B2
- Application number: 17/977,541
- Filed: 2022-10-31
- Published: 2023-03-02
- Granted: 2025-07-22
- Earliest claimed: 2016-01-26
- Assignees: Industrial Technology Research Institute
- Applicants: Industrial Technology Research Institute
- Inventors: Kuo-Kuei Huang; I-Horng Pan; Meng-Nan Lin; Jir-Mehng Lo; Jennline Sheu; Pei-Ru Liau; Yi-Cheng Cheng; Pei-Hsin Lin
- Web page: https://patentgrep.com/patent/US12364731B2

## CPC

- A61K 36/9064: Amomum, e.g. round cardamom
- A61K 9/0019: {Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00)}
- A61K 9/0024: {Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue (compositions for intravenous administration, normal injectable solutions or dispersions for, e.g. subcutaneous administration A61K9/0019; brain implants A61K9/0085; (coated) prostheses, catheters or stents A61L)}
- A61K 9/0053: {Mouth and digestive tract, i.e. intraoral and peroral administration}
- A61K 9/0073: {Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy; (nasal sprays A61K9/0043; inhalation of vapours of volatile or heated drugs, e.g. essential oils or nicotine, A61K9/007; devices A61M)}
- A61K 31/11: Aldehydes
- A61P 1/00: Drugs for disorders of the alimentary tract or the digestive system
- A61P 1/04: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A61P 19/02: for joint disorders, e.g. arthritis, arthrosis
- A61P 25/00: Drugs for disorders of the nervous system
- A61P 37/00: Drugs for immunological or allergic disorders
- A61P 37/02: Immunomodulators
- A61K 2236/333: using mixed solvents, e.g. 70% EtOH
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

A method of treating or alleviating autoimmune-related diseases is provided. The method includes administering a pharmaceutical composition to a subject in need thereof. Moreover, the pharmaceutical composition includes an extract of Amomum tsao-ko as an effective ingredient and a pharmaceutically acceptable carrier or salt.

## Claims

### Claim 1

A method of treating or alleviating psoriasis, comprising:
administering a pharmaceutical composition to a subject in need thereof, wherein the pharmaceutical composition comprises tsaokoin as an effective ingredient and a pharmaceutically acceptable carrier or salt.

### Claim 2 (depends on 1)

The method of treating or alleviating psoriasis as claimed in claim 1, wherein the pharmaceutical composition has the effect on inhibiting cytokine secretion, and the cytokine includes IL-17, TNF-α, and a combination thereof.

### Claim 3 (depends on 1)

The method of treating or alleviating psoriasis as claimed in claim 1, wherein the pharmaceutical composition is administered orally, non-orally, parenterally by an inhalation spray, or via an implanted reservoir.