Microbial compositions to increase the production of PCA from polyphenols
AssigneeChurch & Dwight Co., Inc.
InventorsNoah Paul Zimmerman, Alexandra Helena Smith
Life of this patent
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Abstract
Compositions and methods for converting at least one polyphenol to protocatechuic acid (PCA) using Bacillus subtilis 1579, or active variants thereof, are provided. Conversion of polyphenols, such as quercetin, to PCA can decrease inflammation, decrease cortisol levels, and increase milk quality and milk production quantity in milk-producing agricultural animals. Accordingly, provided herein are compositions comprising B. subtilis 1579, or an active variant thereof, for administration to humans for decreasing inflammation or for administration to milk-producing agricultural animals for decreasing inflammation, decreasing cortisol levels, and increasing milk quality and milk production.
Claims6
A method of increasing the production of protocatechuic acid (PCA) from at least one polyphenol, said method comprising combining said at least one polyphenol with an effective amount of a bacterial strain composition comprising:
- a) Bacillus subtilis 1579 deposited under accession number NRRL B-67952;
- or
- b) a combination of cells with forespores and/or spores of Bacillus subtilis 1579 deposited under accession number NRRL B-67952,
- wherein said effective amount of said bacterial strain composition comprises 105 CFU/gram to 1012 CFU/gram or at 105 CFU/ml to 1012 CFU/ml of Bacillus subtilis 1579.
Dependencies are inferred from the claim text.