Method for producing coated medical device
AssigneeToray Industries, Inc.
InventorsRumiko Kitagawa, Masataka Nakamura
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Abstract
An object of the present invention is to provide a simple method for manufacturing a coated medical device allowed to have not only properties such as sufficient hydrophilicity but also a bacteria adhesion inhibiting capability. The present invention provides a method for manufacturing a coated medical device, including: (A) a contacting step of housing a medical device in a container, and bringing the medical device into contact with a solution a containing a hydrophilic polymer A; and (C) a heating step of heating the container; wherein the hydrophilic polymer A is a polymer containing, as a monomer unit, a compound having a quaternary ammonium cation group; and wherein the pH of the solution a after the heating step is 6.1 to 8.0.
Claims10
A method for manufacturing a coated medical device, comprising:
- (A) a contacting step of housing a medical device in a container, and bringing said medical device into contact with a solution a containing a hydrophilic polymer A;
- and
- (C) a heating step of heating said container;
- wherein said hydrophilic polymer A is a polymer containing, as a monomer unit, a compound a1 having a quaternary ammonium cation group represented by the following general formula (I):
- wherein, in the general formula (I), R1 represents an optionally substituted C1-20 divalent organic group;
- and R2 to R4 each independently represent a C1-16 alkyl group or a C6-18 aryl group;
- wherein said hydrophilic polymer A further contains, as a monomer unit, a compound a2 having a structure represented by the following general formula (II):
- wherein, in the general formula (II), L1 represents a hydrogen atom or a methyl group;
- X represents an oxygen atom or NA2, wherein A2 represents a hydrogen atom or an alkyl group;
- m represents an integer of 1 to 30;
- and Y represents methyl group, ethyl group, propyl group, isopropyl group, or butyl group;
- wherein, with respect to 100% by mass of the whole hydrophilic polymer A, a content of the compound a1 is 5% by mass or more and 90% by mass or less, and a content of the compound a2 is 10% by mass or more and 80% by mass or less;
- and
- wherein the pH of the solution a after said heating step is 6.1 to 8.0.
Dependencies are inferred from the claim text.