Back to results
US 12,359,238 B2Granted
Recombinant flavin-adenine dinucleotide glucose dehydrogenase and uses thereof
AssigneeB. G. Negev Technologies and Applications Ltd., At Ben-Gurion University
InventorsLital Alfonta, Raz Zarivach, Jennifer Grushka, Itay Algov
Life of this patent
Estimating the term…
Abstract
A polypeptide comprising a residue substituted by a non-canonical amino acid (ncAA) is provided. Methods for: (a) transferring an electron to an electrode, by coupling the polypeptide to an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.
Claims17
A recombinant protein, comprising (a) alpha subunit of an FAD-GDH;
- and (b) a minimal c-type cytochrome peptide, wherein said alpha subunit of an FAD-GDH comprises an amino acid sequence comprising a non-canonical amino acid (ncAA), and wherein said sequence is set forth in SEQ ID NO:
- 20 or SEQ ID NO:
- 22.
Dependencies are inferred from the claim text.