Cellular therapy infusion devices, systems, and methods for use

A cellular therapy infusion system comprising:

• an endplate for accepting and holding a cellular therapy infusion device positioned therein in place, the endplate including an exit port configured, arranged, and positioned to allow a catheter coupled to the cellular therapy infusion device to exit the cellular therapy infusion system via the exit port, the cellular therapy infusion device comprising:
• a barrel sized and shaped to accept insertion of a plunger therein and contain a volume of cellular therapy media;
• a gasket positioned on an exterior surface of the barrel;
• a syringe shaft, a first end of the syringe shaft being physically coupled to, and in liquid communication with, the barrel and a second end of the syringe shaft including a catheter coupling configured to couple to the catheter;
• and
• the plunger positioned within the barrel at a first position, the plunger being configured so that when a compressive force is applied to the plunger, the plunger is translated from the first position to a second position thereby pushing the volume of cellular therapy media from the barrel to the syringe shaft;
• a first motor for moving a headplate mechanically coupled thereto;
• the headplate mechanically coupled to the first motor and configured to apply the compressive force to the plunger responsively to movement of the first motor, the compressive force translating the plunger from the first position to the second position;
• a second motor mechanically coupled to and configured to rotate a rotation shaft;
• the rotation shaft being configured to engage the gasket and translate rotation of the rotation shaft by the second motor to the gasket, thereby rotating the barrel;
• and
• a processor configured to control an operation of the first motor and thereby control a magnitude of compressive force applied to the plunger.