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US 12,357,683 B2Granted
Vaccines against Nipah virus, and methods of using same
AssigneeThe Wistar Institute of Anatomy and Biology
InventorsKar Muthumani, David Weiner
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Abstract
An aspect of the present invention is related to nucleic acid constructs capable of expressing at least one Nipah virus (NiV) antigen that elicits an immune response in a mammal against NiV virus, and methods of use thereof.
Claims13
A nucleic acid molecule encoding at least one consensus Nipah virus (NiV) antigen, wherein the nucleic acid molecule comprises a sequence selected from the group consisting of
- a) a nucleotide sequence having at least 98% identity over an entire length of the nucleotide sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:5,
- b) an immunogenic fragment comprising at least 98% identity over at least 60% of the nucleotide sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:5, and
- c) the nucleotide sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:5.
Dependencies are inferred from the claim text.