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AssigneeTzung-Yan
InventorsTzung-Yan Lee, Hen-Hong Chang, Hsuan-Miao Liu, Wei-Han Chiang, Jheng-Huei Wang
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Disclosed herein are pharmaceutical compositions and uses thereof in treating muscle atrophy. The pharmaceutical composition comprises an ethanol extract of an herbal mixture consisting of Artemisia argyi, Morus alba L., Leonurus japonicus Houtt, Capsicum annuum L., Lophatherum gracile Brongn, Curcuma longa, and Glycyrrhiza uralensis; and a pharmaceutically acceptable excipient. The ethanol extract comprise 14 ingredients, including chlorogenic acid, leonurine, schaftoside, rutin, isochaftoside, isochlorogenic acid, 4, 5-dicaffeoylquinic acid, quercetin, apigenin, glycyrrhizic acid, bisdemethoxycurcumin, demethoxycurcumin, curcumin and artemisetin.
A method of treating muscle atrophy in a human in need thereof consisting essentially of administering to the human in need thereof a therapeutically effective amount of an ethanol extract of Artemisia argyi, Morus alba L., Leonurus japonicus Houit, Capsicum annum L., Lophatherm gracile brongn, Curcuma longa and Glycyrrhiza uralensis to effectively treat the muscle atrophy in the human in need thereof.
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