Identification of oleanolic acid and plant extract for glucose-6-phosphate dehydrogenase-related disorders including Bag3opathy
AssigneeHong Kong Baptist University
InventorsZhaoxiang Bian, Tao Hung, Ling Zhao, Lidan Zhong, Chengyuan Lin
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Abstract
A method of treating a glucose-6-phosphate dehydrogenase deregulated disorder in a subject in need thereof, the method involving administering a therapeutically effective amount of oleanolic acid or a conjugate salt thereof or prodrug thereof to the subject. The glucose-6-phosphate dehydrogenase deregulated disorder can be BCL2 associated athanogene myofibrillar myopathy, amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, or Alzheimer disease.
Claims9
A method of treating a glucose-6-phosphate dehydrogenase (G6PD) deregulated disorder in a subject in need thereof, the method comprising administering a therapeutically effective amount of oleanolic acid, a pharmaceutically acceptable salt thereof, or a prodrug thereof to the subject, wherein the G6PD deregulated disorder is BCL2 associated athanogene myofibrillar myopathy Bag3opathy).
Dependencies are inferred from the claim text.