US 12,357,507 B2 · Radiation dosimetry systems and methods

Abstract

In some examples, a laser-based ophthalmological surgical system (hereinafter “system”) includes a therapeutic radiation source configured to emit therapeutic radiation with a first wavelength. The system may also include a probe radiation source configured to emit probe radiation with a second wavelength different than the first wavelength. The system may also include one or more optical elements configured to direct the therapeutic radiation and the probe radiation into an eye of a patient and to collect reflected probe radiation from the eye of the patient. The reflected probe radiation may be indicative of an amount of therapeutic radiation exposure of the eye of the patient. The system may also include a photodetector configured to receive the reflected probe radiation from the one or more optical elements and to generate a photocurrent indicative of the amount of therapeutic radiation exposure of the eye of the patient.

Claims20

Dependent claims

A laser-based ophthalmological surgical system, comprising:

a therapeutic radiation source configured to emit therapeutic radiation with a first wavelength;
a probe radiation source configured to emit probe radiation with a second wavelength different than the first wavelength;
one or more optical elements configured to direct the therapeutic radiation and the probe radiation into an eye of a patient and to collect reflected probe radiation from the eye of the patient, the reflected probe radiation being indicative of an amount of therapeutic radiation exposure on the eye of the patient;
a photodetector configured to receive the reflected probe radiation from the one or more optical elements and to generate a photocurrent indicative of the amount of therapeutic radiation exposure on the eye of the patient;
and
an acquisition circuit electrically coupled to the photodetector and configured to gate the photodetector according to expected time intervals of microbubble formation and/or bursting of microbubbles in the eye of the patient.

3 more elements

A method to measure therapeutic radiation dosimetry, the method comprising:

irradiating an eye of a patient with therapeutic radiation with a first wavelength, wherein the therapeutic radiation causes microbubbles to form on melanosomes of retinal pigment epithelial (RPE) cells of the eye of the patient;
irradiating the eye of the patient with probe radiation with a second wavelength different than the first wavelength;
collecting reflected probe radiation from the eye of the patient;
generating a photocurrent from the collected reflected probe radiation, the photocurrent being indicative of an amount of therapeutic radiation exposure of the eye of the patient;
and
gating the generating of the photocurrent according to expected time intervals of microbubble formation.

3 more elements

Dependencies are inferred from the claim text.

Radiation dosimetry systems and methods

Life of this patent

Radiation dosimetry systems and methods

Life of this patent

Abstract

Claims20