Bioresorbable, implantable device having controlled drug delivery
OwnerJohn James Scanlon, Catherine Ann Scanloninventors
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Abstract
A bioresorbable, implantable device having controlled drug delivery is disclosed herein. The bioresorbable, implantable device is configured as a film, a roll, a tube, and a stent. The bioresorbable, implantable device is configured to release an active ingredient (the “drug”) from the bioresorbable, implantable device when the bioresorbable, implantable device is implanted within a body. The bioresorbable, implantable device is configured to control the onset of the release of the drug, the sequence of drug delivery, and the duration of drug delivery by embedding the drug within at least one therapeutic layer positioned within bioresorbable, implantable device.
Claims15
A preform of a medical implant, comprising:
- (a) a release media;
- and
- (b) a film layer having a surface peelably bonded to a surface of the release media without an adhesive layer disposed between the surfaces of the release media and the film layer, such that the film layer is removable from the release media by lifting an edge of the film layer and peeling the film layer off the release media,
- wherein the film layer as presented on the surface of the release media comprises an amorphous bioresorbable polymer with a degree of crystallinity of less than 25% and having a weight average molecular weight of 16 kg/mol to 3,000 kg/mol as measured by Gel Permeation Chromatography (GPC) in chloroform at 35 degrees Celsius relative to polystyrene standards, and
- wherein the film layer is configured to be formable into shapes of a variety of different medical implants for different medical applications, after removal of the film layer from the release media, by manipulation of the film layer.
Dependencies are inferred from the claim text.