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US 12,356,981 B2Granted
Cell freezing medium for clinical use
AssigneeAbelzeta Inc.
InventorsFei Wang, Jiaping He, Dijun Zhao, Victor Liu, Dingzhu Yang
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AssigneeAbelzeta Inc.
InventorsFei Wang, Jiaping He, Dijun Zhao, Victor Liu, Dingzhu Yang
Estimating the term…
Provided in the present invention is a cell freezing medium for clinical use. In particular, the cell freezing medium of the present invention comprises the following components: (1) human albumin; (2) cryoprotectant: the cryoprotectant comprises a combination of one or more of dimethyl sulfoxide, glycerol, and ethylene glycol; (3) a saline buffer; wherein the salt buffer is a solution containing Na+, K+, Mg+, Cl−, and CH3COO− ions; (4) a vitamin; and (5) an amino acid, wherein the human albumin concentration is 1%-20% (w/v). The cell, after long-term cryopreservation with the freezing medium of the present invention, has a high viability, and the cellular efficiency maintains a high uniformity. The grade of purity of the freezing medium of the present invention is the pharmaceutical grade or USP grade; and the freezing medium is safe and reliable for clinical use, and can be used or conventional adherent and suspension cells.
A cell cryopreservation solution for long-term storage of a mammalian stem cell, comprising:
Dependencies are inferred from the claim text.