Fluorescence-based detection of problematic cellular entities

A system for examining a target, the system comprising:

• a processor configured to:
• receive a fluorescence-based image of the target and a thermal image of the target from a device coupled to the system, wherein the device comprises:
• a first light source for emitting light for illuminating the target that causes a marker in the target to fluoresce;
• an image sensor configured to directly receive light emitted by the target in response to the illumination thereof by the first light source without an optical bandpass filter being disposed between the image sensor and the target, and to capture the fluorescence-based image formed based on the light emitted, wherein the fluorescence-based image comprises fluorescence emerging from the target;
• and
• a thermal sensor configured to obtain the thermal image of the target, wherein the thermal image comprises thermal radiation emerging from the target;
• analyze, using an analysis model, the fluorescence-based image and the thermal image;
• detect, using the analysis model, presence of a problematic cellular entity in the target based on the analysis of the fluorescence-based image and the thermal image, wherein the analysis model is trained for detecting the presence of problematic cellular entities in targets;
• and
• transmit, to the device, a result corresponding to the detection.

A method for examining a target, the method comprising:

• illuminating the target using a first light source of a device, wherein the illumination is to cause a marker in the target to fluoresce;
• capturing, by an image sensor of the device, a fluorescence-based image, wherein the image sensor is operable to directly receive light emitted by the target in response to the illumination thereof by the first light source without an optical bandpass filter being disposed between the image sensor and the target, wherein the fluorescence-based image is formed based on the light emitted by the target, and wherein the fluorescence-based image comprises fluorescence emerging from the target;
• analyzing, by a processor of the device, a fluorescence-based image and a thermal image using an analysis model, wherein the fluorescence-based image comprises fluorescence emerging from the target in response to light emitted by the first light source, and wherein the thermal image comprises thermal radiation emerging from the target;
• and
• detecting, by the processor, presence of a problematic cellular entity in the target using the analysis model based on the analysis of the fluorescence-based image and the thermal image, wherein the analysis model is trained for detecting the presence of problematic cellular entities in targets.