Borohydride reduction stabilizing system and method for reducing ester to alcohol
AssigneeAsymchem Laboratories (Tianjin) Co., Ltd.
InventorsHao Hong, Jiangping Lu, Enxuan Zhang, Zhiqing Liu, Tao Zhang
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AssigneeAsymchem Laboratories (Tianjin) Co., Ltd.
InventorsHao Hong, Jiangping Lu, Enxuan Zhang, Zhiqing Liu, Tao Zhang
Estimating the term…
Disclosed are a borohydride reduction stabilizing system and a method for reducing an ester to an alcohol. The borohydride reduction stabilizing system includes: a borohydride reducing agent and a stabilizing agent for stabilizing the borohydride reducing agent. The borohydride reducing agent is sodium borohydride or potassium borohydride. The stabilizing agent is an alkali metal salt of an alcohol. By adding the alkali metal salt of the alcohol, such as sodium alkoxide or potassium alkoxide, on the basis of an existing sodium/potassium borohydride reducing agent, the sodium/potassium borohydride reducing agent may be kept stable without being decomposed under the condition of increased temperature, so that on the one hand, the reducing activity is maintained in a relatively high state, and the condition of excessive use is reduced, and on the other hand, the generation of hydrogen is reduced, and the process risks are reduced.
A method for reducing an ester to an alcohol, wherein the method comprises reducing an ester to an alcohol with a borohydride reduction stabilizing system,
Dependencies are inferred from the claim text.