US 12,350,398 B2 · Biodegradable bone glue

Abstract

The present invention is directed to bioresorbable polymers to be used as bone and tissue adhesives. The present invention is also directed to the synthesis of bioresorbable polymeric molecules bearing adhesive moieties and the use of such compounds in methods to glue and stabilize fractured bones and damaged tissues. The present invention is also directed to the use of such compounds as adhesive sealants for applications in wound care. The present invention is also directed to the use of such compounds as biodegradable ink for applications in tissue engineering and 3D printing. The present invention also relates to the use of such compounds as drug delivery platforms.

Claims2

Dependent claims

A method for filling void spaces within biological tissues comprising administering an amount of the composition comprising:

a bioresorbable polymer of Formula I, or a mixture thereof;
a solvent;
and
a non-solvent
to the void spaces within biological tissues;
and wherein Formula I is:
wherein:
R is:
2 TEA;
or
wherein:
m is between 4 and 90;
n is between 5 and 200;
x is between 1 and 200;
and
y is between 0 and 200.

13 more elements

Dependencies are inferred from the claim text.

Facts

Application

18/139,764Filed 26 Apr 2023 · division

Priority

28 Apr 2017

Published

US 2023/0310696 A15 Oct 2023

Granted

8 Jul 2025

Term ends

Not estimatedThe source records don’t support an estimate.

Classification33 codes

A61L 24/0042
Use of materials characterised by their function or physical properties: materials resorbable by the body
A61B 17/00491
Surgical instruments, devices or methods: surgical glue applicators
A61F 2/0095
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting…:…
A61L 24/0015
Use of materials characterised by their function or physical properties: medicaments; Biocides

Family

Application62/491,665Us provisional application · filed 28 Apr 2017

PCT/EP2018/060965Parent of this division · filed 27 Apr 2018

US 11,642,436 B2Parent of this division · filed 9 May 2023

US 2023/0310696 A1Pre-grant publication · published 5 Oct 2023

Application16/608,830Parent of this division

US 2020/0197562 A1Published application

US 12,350,398 B2This patent

From the US filing history. Foreign family members aren’t listed.

Biodegradable bone glue

Life of this patent

Biodegradable bone glue

Life of this patent

Abstract

Claims2