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US 12,350,353 B2Granted
Synthetic enamel and uses thereof
AssigneeTrustees of Boston University
InventorsYuwei Fan, Lina Fahad N. Mengari, Zhi Sun
Life of this patent
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Abstract
The present disclosure relates to compositions and methods for restoring enamel, e.g., on tooth surfaces.
Claims22
A remineralization composition comprising:
- a. calcium in a concentration from about 0.1 mM to about 500 mM;
- b. phosphate in a concentration from about 0.1 mM to about 100 mM;
- and
- c. fluoride in a concentration from about 0.2 ppm to about 300 ppm,
- wherein the composition has a pH of from no less than 7.1 to about 8, and an ionic strength of from about 50 mM to about 500 mM, and
- wherein the remineralization composition further comprises:
- (i) strontium in a concentration about 0.05 ppm to about 300 ppm;
- or (ii) stannous in a concentration from about 0.1 ppm to about 50 ppm.
5 more elements
Dependencies are inferred from the claim text.