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US 12,350,329 B2Granted
RNA vaccines against infectious diseases
AssigneeHDT Bio Corp.
InventorsSteven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
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Abstract
The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using these compositions as a vaccine for treatment of an infectious disease are also provided.
Claims18
A composition comprising:
- a lipid carrier, wherein the lipid carrier comprises:
- liquid oil;
- a cationic lipid;
- a hydrophilic surfactant;
- and
- a hydrophobic surfactant;
- and
- nucleic acids, wherein the nucleic acids comprise a sequence encoding for an antigen from an influenza virus, wherein the sequence is at least 85% identical to SEQ ID NO:
- 3.
6 more elements
Dependencies are inferred from the claim text.