DNA aptamers specific of adenovirus types
AssigneeLuxembourg Institute of Science and Technology (List)
InventorsLeslie Ogorzaly, Samuel Jourdan, Catherine Mulholland
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Abstract
A single stranded nucleic acid aptamer able to specifically bind to at least one Adenovirus type, the aptamer comprising or consisting of one of sequences SEQ ID NO:1 to 3, or variants thereof having at least 50% sequence identity. Additionally, a composition comprising the aptamer. Furthermore, use of the aptamer, for detecting, capturing, concentrating and/or quantifying at least one Adenovirus type. Still further, in vitro methods for capturing, detecting and/or quantifying at least one Adenovirus type. Further yet, a kit for detecting, quantifying, capturing and/or concentrating at least one Adenovirus type.
Claims13
A single stranded nucleic acid aptamer able to bind specifically to at least one adenovirus type, said aptamer comprising at least one of sequences SEQ ID NO:
- 1 to 3.
A composition comprising at least one single stranded nucleic acid aptamer able to bind specifically to at least one adenovirus type, said aptamer comprising at least one of sequences SEQ ID NO:
- 1 to 3 and at least one adenovirus type.
An in vitro method for capturing at least one adenovirus type in a sample, comprising the step of contacting the sample with a single strand nucleic acid aptamer able to bind specifically to at least one adenovirus type, said aptamer comprising at least one of sequences SEQ ID NO:
- 1 to 3.
An in vitro method for at least one of detecting and quantifying at least one adenovirus type in a sample, comprising:
- in vitro capturing of at least one adenovirus type in a sample by contacting the sample with a single strand nucleic acid aptamer able to bind specifically to at least one adenovirus type, said aptamer comprising at least one of sequences SEQ ID NO:
- 1 to 3;
- one of quantifying or detecting one of the presence or absence of bound aptamer to adenovirus;
- deducing therefrom one of the amount or the presence or the absence of adenovirus in the sample.
A kit for at least one of detecting, quantifying, capturing and concentrating at least one adenovirus type comprising at least one single strand of nucleic acid aptamer able to bind specifically to at least one adenovirus type, the aptamer comprising at least one of sequences SEQ ID NO:
- 1 to 3.
Dependencies are inferred from the claim text.