Respiratory syncytial virus recombinant F protein and vaccine composition containing same

A recombinant fusion protein (F protein) of respiratory syncytial virus (RSV), wherein:

• a polymerization domain derived from a heterologous protein is linked at the C-terminus of a fusion protein (F protein) with the transmembrane domain of the wild-type respiratory syncytial virus (RSV) fusion protein (F protein) deleted;
• the polymerization domain derived from a heterologous protein is a polypeptide, and the polypeptide is a bacteriophage T4 fibritin foldon domain polypeptide having SEQ ID NO:
• 23;
• and
• the fusion protein (F protein) with the transmembrane domain of the wild-type respiratory syncytial virus (RSV) fusion protein (F protein) deleted has an amino acid sequence selected from SEQ ID NOS:
• 3-22.