Anti-adhesive hydrogel composition
AssigneeThe Governing Council of the University of Toronto
InventorsMolly Shoichet, Michael J. Cooke
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Abstract
A method of reducing or limiting tissue adhesion comprises contacting the tissue with an effective amount of a hydrogel composition comprising: 2% to 6% by weight hyaluronan, and 3% to 18% by weight methylcellulose, wherein the combined total amount of hyaluronan and methylcellulose in the hydrogel is between 8 and 24% by weight; and wherein the ratio of hyaluronan:methylcellulose is between 1:1 and 1:5 w/w. The hydrogel composition and may be used to reduce or limit tissue adhesion that is correlated with surgery, and may be used in surgeries wherein the surgery is performed through a small incision or opening.
Claims18
A method of reducing or limiting tissue adhesion comprising
- contacting the tissue with an effective amount of a hydrogel composition comprising:
- 2% to 6% by weight hyaluronan, and
- 3% to 18% by weight methylcellulose,
- wherein the combined total amount of hyaluronan and methylcellulose in the hydrogel is between 8 and 24% by weight;
- and wherein the ratio of hyaluronan:methylcellulose is between 1:1 and 1:5 w/w.
Dependencies are inferred from the claim text.