Back to results
US 12,343,450 B2Granted
Biologic filler for restoring and regenerating tissue
AssigneeGeniphys, Inc.
InventorsSherry L. Voytik-Harbin, Theodore J. Puls
Life of this patent
Estimating the term…
Abstract
Compositions and methods for filling tissue voids and defects with a self-assembling biopolymer configured to form a shape-retaining matrix are described.
Claims19
A method for filling a tissue void formed by the surgical removal of soft tissue from a patient, the method comprising:
- introducing into the tissue void a polymerizable collagen composition comprising a solution of oligomeric collagen in an amount to fill the void;
- and polymerizing the polymerizable collagen composition in situ to form a shape-retaining collagen scaffold having viscoelastic properties similar to soft tissues.
A method for filling a tissue void in the breast tissue of a patient, wherein the tissue void is generated by a lumpectomy or mastectomy procedure, said method comprising the steps of
- introducing into the tissue void a polymerizable collagen composition in an amount to fill the void, said polymerizable collagen composition comprising
- a solution of oligomeric collagen comprising about 7 mg/mL to about 8 mg/mL oligomeric collagen, based on a dry weight of the oligomeric collagen;
- and
- a buffer solution,
- polymerizing the polymerizable collagen composition in situ to form a shape-retaining collagen scaffold having viscoelastic properties similar to soft tissues.
2 more elements
Dependencies are inferred from the claim text.