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US 12,342,842 B2Granted
Preparation for use in enhancing formation of short-chain fatty acids (SCFAs)
AssigneeEvonik Operations GmbH
InventorsBodo Speckmann, Michael Schwarm, Ines Ochrombel, Stefan Pelzer
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Abstract
The invention discloses preparations for use in enhancing formation of short-chain fatty acids (SCFAs) in a subject for treating or preventing a disease or disorder comprising at least one omega-3 fatty acid salt having an organic counter ion selected from lysine, arginine, ornithine, choline and mixtures of the same, wherein the omega-3 fatty acid is selected from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and a colon-specific delivery system.
Claims17
A colonic preparation, comprising:
- an omega-3 fatty acid salt having an organic counter ion selected from the group consisting of lysine, arginine, ornithine, choline, and a combination thereof;
- and
- a colon-specific delivery system selected from the group consisting of a delivery system comprising a coating with a pH dependent polymer, a delivery system comprising a coating with a pH independent biodegradable polymer, and a delivery system based on a metabolic activity of a colonic bacteria,
- wherein the omega-3 fatty acid is selected from the group consisting of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and
- wherein the preparation is a powder having a mean particle size of 1 μm or less.
2 more elements
Dependencies are inferred from the claim text.