Back to results
US 12,338,435 B2Granted
Nucleic acid carriers and therapeutic methods of use
AssigneeCode Biotherapeutics, Inc.
InventorsRobert C. Getts, James M. Kadushin, Lori Getts
Life of this patent
Estimating the term…
Abstract
The present disclosure provides nucleic acid carriers comprising targeting agents, pharmaceutical compositions comprising the same, and methods of making and using the same.
Claims7
A nucleic acid carrier comprising a first and a second oligonucleotide:
- wherein a central portion of each of the first and second oligonucleotides is complementary to each other, forming a double-stranded region, wherein the double-stranded region is from about 25 to about 35 bases in length;
- wherein the two terminal portions of the first oligonucleotide are not complementary to the two terminal portions of the second oligonucleotide, forming four single-stranded arms;
- and
- an antibody, conjugated to at least one single-stranded arm of the four single-stranded arms.
1 more element
Dependencies are inferred from the claim text.