Method for manufacturing oxygenator
AssigneeTerumo Kabushiki Kaisha
InventorsRenjo Takama, Takeshi Sato
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Abstract
An oxygenator has a plurality of porous hollow fiber membranes comprising polypropylene for gas exchange, wherein each hollow fiber membrane has an inner surface that forms a lumen and an outer surface. The oxygenator is manufactured using a method which involves preparing a coating solution containing at least one compound selected from the group consisting of dopamine, salt of dopamine, and oligomer of dopamine; and bringing the inner surface or the outer surface of the hollow fiber membranes into contact with the coating solution for less than ten hours while blowing oxygen gas in the coating solution to form a dopamine polymer layer containing a polymer of the compound on the inner surface or the outer surface.
Claims20
A method for manufacturing an oxygenator having a plurality of porous hollow fiber membranes for gas exchange comprised of polypropylene, wherein each hollow fiber membrane has an inner surface that forms a lumen and an outer surface, wherein the method comprises the steps of:
- preparing a coating solution containing at least one compound selected from the group consisting of dopamine, salt of dopamine, and oligomer of dopamine;
- and
- bringing the inner surface or the outer surface of the hollow fiber membranes into contact with the coating solution for less than ten hours while blowing oxygen gas in the coating solution to form a dopamine polymer layer containing a polymer of the compound on the inner surface or the outer surface.
An oxygenator for treating blood, comprising:
- a plurality of porous hollow fiber membranes for gas exchange each of which has an inner surface and an outer surface;
- and
- a housing which directs the blood to one of the inner surfaces or the outer surfaces and which directs a gas to the other one of the inner surfaces or the outer surfaces;
- wherein the inner surfaces or the outer surfaces which receive the blood are provided with a dopamine polymer layer which is formed by (1) preparing a coating solution containing at least one compound selected from the group consisting of dopamine, salt of dopamine, and oligomer of dopamine, and (2) bringing the hollow fiber membranes into contact with the coating solution for less than ten hours while blowing oxygen gas in the coating solution.
Dependencies are inferred from the claim text.