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US 12,337,030 B2Granted
Viral vector
AssigneeValo Therapeutics Oy
InventorsVincenzo Cerullo, Cristian Capasso, Sara Feola, Siri Tahtinen
Life of this patent
Estimating the term…
Abstract
The invention concerns a novel viral vector with modified viral capsid or viral envelope; a pharmaceutical composition or immunogenic agent or vaccine comprising same; a target cell transformed or transfected with same; a combination therapeutic comprising same; use of same in treatment of cancer, and a method of treating cancer using same.
Claims20
A viral vector having attached to its viral capsid or envelope, polypeptides that are not genetically encoded by said viral vector but are attached to the capsid or envelope covalently or non-covalently, wherein:
- i) at least one of said polypeptides comprises an antigen from, or of, a pathogen that a subject has been prior immunised against;
- and
- ii) at least one other of said polypeptides is a tumor or cancer specific polypeptide and so stimulates an anti-tumor or anti-cancer immune response in a subject exposed to said vector.
Dependencies are inferred from the claim text.