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US 12,331,342 B2Granted
Linalool synthases
AssigneeC3 Biotechnologies Limited
InventorsNigel Scrutton, Nicole Leferink
Life of this patent
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Abstract
Linalool synthase variants are disclosed. The variants preferably comprise an amino acid sequence having one or more amino acid substitutions. Variants producing a greater linalool yield and/or higher linalool:nerolidol ratio compared with the corresponding wild type linalool synthase are also disclosed. A method comprising the conversion of geranyl pyrophosphate to linalool using a linalool synthase variant is also disclosed.
Claims21
A linalool synthase comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence of SEQ ID NO:
- 1, and an amino acid substitution corresponding to one or more of L72 and V214 relative to SEQ ID NO:1.
Dependencies are inferred from the claim text.